{"id":1169,"date":"2025-11-03T14:04:21","date_gmt":"2025-11-03T14:04:21","guid":{"rendered":"https:\/\/chromrare.eu\/?p=1169"},"modified":"2025-11-03T14:04:23","modified_gmt":"2025-11-03T14:04:23","slug":"maulana-ariefai","status":"publish","type":"post","link":"https:\/\/chromrare.eu\/index.php\/2025\/11\/03\/maulana-ariefai\/","title":{"rendered":"Maulana Ariefai"},"content":{"rendered":"<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"1024\" src=\"https:\/\/chromrare.eu\/wp-content\/uploads\/2025\/11\/Mulana-1-768x1024.jpeg\" alt=\"\" class=\"wp-image-1170\" srcset=\"https:\/\/chromrare.eu\/wp-content\/uploads\/2025\/11\/Mulana-1-768x1024.jpeg 768w, https:\/\/chromrare.eu\/wp-content\/uploads\/2025\/11\/Mulana-1-225x300.jpeg 225w, https:\/\/chromrare.eu\/wp-content\/uploads\/2025\/11\/Mulana-1-1152x1536.jpeg 1152w, https:\/\/chromrare.eu\/wp-content\/uploads\/2025\/11\/Mulana-1.jpeg 1200w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \/><\/figure>\n<\/div>\n\n\n<p class=\"has-text-align-center has-medium-font-size\">Hey everyone! I\u2019m Maulana Ariefai, a ChromRare PhD student at the University of<br>Trento, working in Prof. Alessio Zippo\u2019s Chromatin Biology &amp; Epigenetics group.<br>Our team is passionate about understanding how epigenetic changes affect stem<br>cells \u2014 both in normal and disease conditions. In my project, I focus on CHD7, a<br>fascinating protein whose mutations are linked to CHARGE syndrome, a rare<br>developmental disorder.<br>We believe that the way CHD7 forms tiny liquid-like \u201ccondensates\u201d inside the nucleus<br>is crucial for keeping cells healthy. When this process goes wrong, it might trigger<br>disease. To study this, I use super-resolution microscopy (dSTORM) \u2014 which lets us<br>see structures as small as 10 nanometres \u2014 and single-particle tracking to follow<br>CHD7\u2019s movements in living cells.<br>It\u2019s challenging work, but incredibly exciting! Every image and dataset brings me a bit<br>closer to understanding how our genome\u2019s organization impacts life and disease. My<br>hope is that one day, our findings will inspire new therapeutic strategies for CHARGE<br>syndrome patients.<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h4 class=\"wp-block-heading has-text-align-center\">#PhDLife #Chromatin #Epigenetics #MSCA #RareDiseaseResearch<\/h4>\n\n\n\n<h4 class=\"wp-block-heading has-text-align-center\">#MolecularBiology #UniversityOfTrento<\/h4>\n\n\n\n<p><\/p>\n\n\n\n<h1 class=\"wp-block-heading has-text-align-center\"><\/h1>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Hey everyone! I\u2019m Maulana Ariefai, a ChromRare PhD student at the University ofTrento, working in Prof. Alessio Zippo\u2019s Chromatin Biology &amp; Epigenetics group.Our team is passionate about understanding how epigenetic changes affect stemcells \u2014 both in normal and disease conditions. In my project, I focus on CHD7, afascinating protein whose mutations are linked to CHARGE &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/chromrare.eu\/index.php\/2025\/11\/03\/maulana-ariefai\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Maulana Ariefai&#8221;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_regular_price":[],"currency_symbol":[],"footnotes":""},"categories":[1],"tags":[],"class_list":["post-1169","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"post_slider_layout_featured_media_urls":{"thumbnail":"","post_slider_layout_landscape_large":"","post_slider_layout_portrait_large":"","post_slider_layout_square_large":"","post_slider_layout_landscape":"","post_slider_layout_portrait":"","post_slider_layout_square":"","full":""},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Maulana Ariefai - Chrom_Rare<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/chromrare.eu\/index.php\/2025\/11\/03\/maulana-ariefai\/\" \/>\n<meta property=\"og:locale\" content=\"it_IT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Maulana Ariefai - Chrom_Rare\" \/>\n<meta property=\"og:description\" content=\"Hey everyone! I\u2019m Maulana Ariefai, a ChromRare PhD student at the University ofTrento, working in Prof. Alessio Zippo\u2019s Chromatin Biology &amp; Epigenetics group.Our team is passionate about understanding how epigenetic changes affect stemcells \u2014 both in normal and disease conditions. 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